- 1 How does proin for dogs work?
- 2 What class of drug is proin?
- 3 What are the side effects of proin?
- 4 What is the active ingredient in Proin?
- 5 How quickly does proin work?
- 6 Does proin kill dogs?
- 7 Can proin be stopped abruptly?
- 8 What is the difference between proin and proin ER?
- 9 Do I need a prescription for proin?
- 10 How often should proin be given?
- 11 How much proin can a dog take?
- 12 Why phenylpropanolamine is banned?
- 13 Is proin harmful to humans?
- 14 Why can’t proin be shipped to Oregon?
- 15 Can proin cause anxiety in dogs?
How does proin for dogs work?
The US Food and Drug Administration (FDA) last week approved Proin ER ( phenylpropanolamine hydrochloride extended release), a tablet for the control of urinary incontinence in dogs. The drug will aid with urethral sphincter hypotonus, which occurs due to a dog’s age and weakening muscles in the urethra.
What class of drug is proin?
Therapeutic Classification: PROIN Chewable Tablets (phenylpropanolamine hydrochloride) is a sympathomimetic amine closely related to ephedrine. Phenylpropanolamine hydrochloride is the nonproprietary designation for benzenemethanol, α-(1-aminoethyl)-, hydrochloride, (R*, S*)-, (±).
What are the side effects of proin?
The most commonly reported side effects were vomiting, loss of appetite, diarrhea, excessive salivation, agitation, tiredness, vocalization, confusion, increased water consumption, weight loss, weakness, fever, panting, and reversible changes in skin color (flushing or bright pink).
What is the active ingredient in Proin?
Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.
How quickly does proin work?
Measure liquid forms carefully. Provide access to fresh water at all times. If incontinence occurs at night, give the largest dose at night, before going to sleep. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.
Does proin kill dogs?
Proin is typically safe for otherwise healthy dogs. Because a drug has one effect in humans, does not mean that same effect translates to dogs (or horses or pigs or rabbits.)
Can proin be stopped abruptly?
There have been many cases where owners suddenly and completely halted Proin administration– and their dog was none the worse for it. Though Proin is prescribed mostly for long-term, indeterminate periods, a decrease in dosage may be possible if successful results warrant it.
What is the difference between proin and proin ER?
Proin Chewable Tablets, already approved for use in dogs, are given twice daily for a total daily dose of 2 to 4 mg/kg. The approval of Proin ER, which is dosed once daily at the same total dose rate, gives veterinarians and pet owners an easier option for managing this condition, according to an FDA release.
Do I need a prescription for proin?
What is Proin? Proin is a prescription medication used in the management of urinary incontinence in dogs.
How often should proin be given?
Dosage and Administration The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. PROIN is scored and dosage should be calculated in half-tablet increments.
How much proin can a dog take?
For the control of urinary incontinence due to urethral sphincter hypotonus in dogs. DOSAGE AND ADMINISTRATION: The recommended dosage is 2 to 4 mg/kg (0.9 to 1.8 mg/lb) of body weight once daily according to Table 1 below.
Why phenylpropanolamine is banned?
Phenylpropanolamine has been voluntarily removed from the market in the United States by its manufactures because of concerns raised about its ability to precipitate a stroke when used, or perhaps abused, as an appetite suppressant Kernan et al (2000).
Is proin harmful to humans?
Not for human use. Keep out of the reach of children. Consult with a physician in case of accidental ingestion by humans. Keep PROIN ER™ in a secured location out of the reach of dogs, cats and other animals to prevent accidental ingestion or overdose.
Why can’t proin be shipped to Oregon?
Dosage instructions must be strictly followed. The states of Louisiana, Oregon, Iowa, Illinois and Arkansas classify Proin Chewable Flavor Tabs as a controlled substance so if you are ordering Proin Chewable Flavor Tabs, this can’t usually be shipped to these states.
Can proin cause anxiety in dogs?
The most common adverse reactions are shown in Table 1 below. In addition, one dog exhibited disorientation, nervousness, a 7.7% loss of body weight, and hypertension with proteinuria. A second dog exhibited restless behavior, lethargy, a 2.8% body weight loss and proteinuria.